Tools like Wordpress, Squarespace, Wix, and Webflow let you build a website without knowing HTML or CSS. Most of these tools allow you to create different pages, upload images and media, create a blog, build a form, or set up a shopping cart. These tools generally don't give you control over your application's flow and design, and instead offer templated solutions to common use cases.
Bubble gives you complete control over exactly what happens on your website at every level. Define custom categories of data, take actions such as sending an email or connecting to Facebook, and specify situation-specific logic.
Website builders are great for building simple visual websites with out-of-the-box basic functionality. For everything else, there's Bubble.